Making Antibody Medicines Manufacturing a Reality

Pharmaceutical companies must achieve increased flexibility and agility through better use and monitoring of manufacturing data to improve quality management in real time. Pharmaceutical experts work with Yokogawa to create manufacturing solutions that deliver safe and reliable medicines. Together, we use digital transformation and manufacturing advances to meet regulatory requirements, ensure quality, accelerate time to market, and thus providing a stable and reliable supply of medicine to patient.

The Advanced Control Bioreactor System BR1000 automates lab-scale mammalian cell culture with highly accurate real-time monitoring and advanced process control.

The replacement of manual processes with automation is a trend in the biopharmaceutical industry. For complete automation of fed-batch mammalian cell culture, the control of glucose, a key nutrient source, is critical. Through in-line sensing and model predictive control software, automated feeding and a stable concentration of glucose in bioreactors can be achieved.