Knockout / knock-in of target genes by delivery of genome editing tools

Overview

The SU10 is a “nano” pipette with a tip outer diameter of only a few tens of nanometers, which can automatically deliver target substances into cells (nucleus, cytoplasm) at the single-cell level. The SU10 can directly deliver genome editing tools into the nucleus, so it is expected to enable efficient genome editing. In this application note, we will introduce a case study in which Cas9 RNP and donor DNA were delivered into cells using SU10, resulting in the successful knockout (KO) and knock-in (KI) of target genes.

For further information, download the application note at the top of the page.

Single Cellome Application Note

 

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