Overview
Long-term observation of mitosis by live cell microscopy is required for uncovering the role of Cohesin on compartmentalized nuclear architecture which is linked to nuclear functions.To perform long term observation of mitosis devices are needed that have low phototoxic effects on living cells and enable high speed imaging.
Cohesin, a ring-like protein complex with its major subunits RAD21, SMC1, and SMC3 is involved in sister chromatid entrapment to ensure proper chromosome segregation during mitosis, in double strand break repair and gene regulation Its impact on a compartmentalized nuclear architecture, linked to nuclear functions, is less well understood. By using the CSU W-1 confocal scanner unit for time lapse imaging entrance into mitosis, mitotic progression and exit can be examined.
For further information, download the application note at the top of the page.
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Kapcsolódó termékek és megoldások
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Super Resolution
Super Resolution via Optical Re-assignment.
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Wide Field of View
The CSU-W1 is our answer to researchers’ requests for “Wider FOV” and “Clearer Images”.
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Life Science
Yokogawa’s sensitivity and precision solutions enable rapid and accurate measurements, empowering groundbreaking research, accelerating drug discovery, and optimizing bio-production at scale.
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Spinning Disk Confocal CSU
Using our proprietary dual spinning disk design, Yokogawa’s confocal scanner units transform optical microscopes by enabling real-time live cell imaging.