3D reconstruction of a matured human iPSC-derived brain endothelial microvessel. Florescence staining of Tight-junctions (ZO-1) in green and cytoplasm/nucleus in red (Cellmask). Image acquisition of microvessel (2200 m in length, 300 µm in width and 220 µm in height) was performed by using a 20x air long working distance objective, CellVoyager CV8000, Yokogawa.

Developing a 3D human iPSC-derived Blood-Brain Barrier System on a Chip

Sven Fengler, Ph.D., specializes on assay development at the German Center for Neurodegenerative Diseases (DZNE) Bonn, Germany. Together with his…

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